CJC-1295 DAC
Price on application
CJC-1295 DAC is a long-acting GHRH analog conjugated with a Drug Affinity Complex that binds to serum albumin, extending its half-life to 6-8 days. It provides sustained, elevated GH and IGF-1 levels with less frequent dosing.
Research Profile
CJC-1295 with DAC (Drug Affinity Complex) is a modified GHRH analog that incorporates a maleimidopropionic acid-lysine linker enabling covalent binding to serum albumin after injection. This albumin conjugation dramatically extends the peptide's half-life from minutes to 6-8 days, producing sustained elevations in GH and IGF-1 levels. Clinical studies demonstrated that a single injection could maintain elevated GH levels for up to two weeks. While this extended duration is advantageous for consistent GH elevation, it bypasses the natural pulsatile release pattern, which differentiates it from the non-DAC variant.
Technical Details
- Chemical Formula
- C165H271N47O46
- Synonyms
- CJC-1295 with DAC, DAC:GRF
- Molecular Weight
- 3647.28 g/mol
- CAS Number
- 863288-34-0
- Appearance
- Lyophilized White Powder
- Purity
- >98% (HPLC Verified)
- Shelf Life
- 36 months (Store at -20°C)