Dihexa
Price on application
Dihexa is a synthetic hexapeptide analog of angiotensin IV with extraordinary nootropic potency. It is approximately 10 million times more potent than BDNF at promoting hepatocyte growth factor (HGF) signaling and synaptogenesis.
Research Profile
Dihexa (N-hexanoic-Tyr-Ile-(6) aminohexanoic amide) was developed at Washington State University by Dr. Joseph Harding's laboratory. It is a modified derivative of angiotensin IV that acts as a potent agonist of hepatocyte growth factor (HGF) through its receptor c-Met. By stabilizing HGF and facilitating its binding to c-Met, Dihexa promotes neuronal synaptogenesis, dendritic spine formation, and synaptic plasticity. In preclinical models, it has demonstrated the ability to rescue cognitive deficits in animal models of Alzheimer's disease and other neurodegenerative conditions. Its remarkable potency and oral bioavailability distinguish it from other nootropic peptides, making it a leading compound in cognitive enhancement and neuroprotection research.
Technical Details
- Chemical Formula
- C21H36N4O5
- Synonyms
- Dihexa, N-hexanoyl-Tyr-Ile-(6)-aminohexanoic amide
- Molecular Weight
- 412.53 g/mol
- CAS Number
- 1401708-83-5
- Appearance
- Lyophilized White Powder
- Purity
- >98% (HPLC Verified)
- Shelf Life
- 36 months (Store at -20°C)