DSIP (Delta Sleep Inducing Peptide)
Price on application
DSIP is a naturally occurring nonapeptide that modulates sleep architecture, stress response, and neuroendocrine function. It promotes delta-wave (deep) sleep without acting as a sedative, preserving normal sleep-wake transitions.
Research Profile
Delta Sleep Inducing Peptide (DSIP) was first isolated from the cerebral venous blood of rabbits during electrically induced sleep. This nonapeptide crosses the blood-brain barrier and modulates multiple neuroendocrine pathways. Rather than inducing sedation, DSIP promotes physiological sleep architecture by increasing delta-wave activity during sleep. It has demonstrated stress-protective properties by normalizing cortisol and ACTH levels, exhibits analgesic effects through modulation of enkephalinase activity, and shows anticonvulsant properties. DSIP has also been investigated for its potential to normalize disturbed sleep patterns, reduce withdrawal symptoms, and modulate circadian rhythms.
Technical Details
- Chemical Formula
- C35H48N10O15
- Synonyms
- DSIP, Delta Sleep Inducing Peptide
- Molecular Weight
- 848.81 g/mol
- CAS Number
- 62568-57-4
- Sequence
- Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
- Appearance
- Lyophilized White Powder
- Purity
- >98% (HPLC Verified)
- Shelf Life
- 36 months (Store at -20°C)