Epithalon (Epitalon)
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Epithalon is a synthetic tetrapeptide based on the natural pineal gland peptide Epithalamin. It is primarily researched for its ability to activate telomerase, the enzyme responsible for maintaining telomere length, with implications for aging and cellular longevity.
Research Profile
Epithalon (Ala-Glu-Asp-Gly) was developed by Professor Vladimir Khavinson at the Saint Petersburg Institute of Bioregulation and Gerontology. It is a synthetic version of Epithalamin, a peptide naturally produced by the pineal gland. Epithalon's primary mechanism of action involves the activation of telomerase in somatic cells, enabling the elongation of telomeres — the protective caps on chromosomal ends that shorten with each cell division. In preclinical and clinical studies, Epithalon has demonstrated the ability to increase telomere length, normalize circadian melatonin rhythms, improve immune function, and extend lifespan in animal models. These properties make it a central compound in longevity and anti-aging research.
Technical Details
- Chemical Formula
- C14H22N4O9
- Synonyms
- Epitalon, Epithalamin, Epithalone
- Molecular Weight
- 390.35 g/mol
- CAS Number
- 307297-39-8
- Sequence
- Ala-Glu-Asp-Gly
- Appearance
- Lyophilized White Powder
- Purity
- >98% (HPLC Verified)
- Shelf Life
- 36 months (Store at -20°C)