Follistatin 344
Price on application
Follistatin 344 is the full-length recombinant form of human follistatin, a glycoprotein that binds and neutralizes activin and myostatin. By inhibiting these TGF-β superfamily members, it removes natural brakes on muscle growth.
Research Profile
Follistatin 344 is the 344-amino acid isoform (FS344) of human follistatin, produced through recombinant technology. It functions primarily as a binding protein for activin, myostatin, and other TGF-β superfamily ligands, effectively neutralizing their biological activity. By sequestering myostatin — the body's primary negative regulator of skeletal muscle mass — Follistatin 344 permits enhanced muscle hypertrophy beyond normal physiological limits. Animal studies involving follistatin overexpression have produced dramatic increases in muscle mass (up to 2-3 fold). Beyond muscle biology, follistatin plays roles in reproductive physiology, liver protection, and inflammatory regulation. Its large molecular size and recombinant origin make it one of the most complex peptide products in the research catalog.
Technical Details
- Synonyms
- FS-344, Follistatin, Activin-Binding Protein
- Molecular Weight
- ~38,000 g/mol (38 kDa)
- Appearance
- Lyophilized White Powder
- Purity
- >97% (SDS-PAGE)
- Shelf Life
- 24 months (Store at -20°C)