Photo pendingGW-0742
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GW-0742 is a highly selective PPARδ agonist structurally related to Cardarine (GW-501516). It demonstrates superior receptor selectivity and has been researched for its effects on lipid metabolism, inflammation, and endurance.
Research Profile
GW-0742 is a thiazole-based PPARδ agonist that exhibits approximately 10-fold greater selectivity for PPARδ over PPARα and PPARγ compared to GW-501516. This enhanced selectivity translates to more targeted metabolic effects, including upregulation of fatty acid oxidation genes, improvement of lipid profiles, and increased mitochondrial biogenesis. In preclinical models, GW-0742 has shown significant anti-inflammatory properties, particularly in cardiovascular and pulmonary tissue. It has been investigated as a research tool for studying metabolic syndrome, atherosclerosis, and exercise mimetic pathways.
Technical Details
- Chemical Formula
- C21H17F4NO3S2
- Synonyms
- GW-0742, GW610742
- Molecular Weight
- 471.49 g/mol
- CAS Number
- 317318-84-6
- PubChem ID
- 9803963
- Active Ingredient
- 350mg (10mg per capsule)
- Shelf Life
- 36 months