Semax
Price on application
Semax is a synthetic heptapeptide derived from ACTH(4-7) with an attached Pro-Gly-Pro group. It is a potent nootropic and neuroprotective peptide that enhances cognitive function, memory, and attention without hormonal side effects.
Research Profile
Semax was developed at the Institute of Molecular Genetics in Moscow as a modified fragment of adrenocorticotropic hormone (ACTH). While it retains the ACTH(4-7) core sequence (Met-Glu-His-Phe), the Pro-Gly-Pro tail confers metabolic stability without activating the adrenal axis. Semax enhances BDNF and NGF expression, modulates dopaminergic and serotonergic systems, and promotes neuronal survival under ischemic conditions. It has been approved in Russia for treatment of stroke, cognitive disorders, and optic nerve diseases. Research applications include investigation of neuroplasticity, cognitive enhancement, neuroprotection, and cerebrovascular function.
Technical Details
- Chemical Formula
- C37H51N9O10S
- Synonyms
- Semax, ACTH(4-7)-PGP
- Molecular Weight
- 813.91 g/mol
- CAS Number
- 80714-61-0
- Sequence
- Met-Glu-His-Phe-Pro-Gly-Pro
- Appearance
- Lyophilized White Powder
- Purity
- >98% (HPLC Verified)
- Shelf Life
- 36 months (Store at -20°C)