Sermorelin
Price on application
Sermorelin is a synthetic analog of growth hormone-releasing hormone (GHRH) consisting of the first 29 amino acids of the 44-amino acid native GHRH. It stimulates the pituitary to produce and secrete growth hormone in a physiologically natural pulsatile pattern.
Research Profile
Sermorelin (GRF 1-29 NH2) is the shortest fully functional fragment of GHRH that retains full biological activity at the GHRH receptor. Unlike exogenous GH administration, Sermorelin stimulates the endogenous production and secretion of GH, preserving the body's natural feedback mechanisms and pulsatile release patterns. This physiological approach results in more balanced IGF-1 levels without the supraphysiological spikes associated with direct GH injection. Sermorelin has been FDA-approved for diagnostic use and has been extensively studied for applications in age-related GH decline, pediatric growth disorders, and metabolic optimization.
Technical Details
- Chemical Formula
- C149H246N44O42S
- Synonyms
- Sermorelin Acetate, GRF 1-29 NH2, Geref
- Molecular Weight
- 3357.93 g/mol
- CAS Number
- 86168-78-7
- Sequence
- Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2
- Appearance
- Lyophilized White Powder
- Purity
- >99% (HPLC Verified)
- Shelf Life
- 36 months (Store at -20°C)