Ipamorelin is a pentapeptide and a selective agonist of the ghrelin/growth hormone secretagogue receptor. It is recognized in clinical research for its ability to stimulate growth hormone (GH) secretion without significantly affecting prolactin, ACTH, or cortisol levels, making it one of the most targeted secretagogues available.
Ipamorelin belongs to the most recent generation of GH secretagogues (GHSs). As a pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2), it mimics the action of ghrelin by binding to the ghrelin receptor in the pituitary gland. This interaction triggers a pulse of growth hormone release that mimics natural physiological rhythms.
Research indicates that Ipamorelin supports lean muscle mass preservation, body fat reduction, and improved recovery times. Because of its high selectivity, it does not induce the "hunger spike" often associated with GHRP-6, nor does it impact stress hormones, allowing for a more controlled research environment regarding metabolic and endocrine studies.
Chemical Formula: C38H49N9O5
Synonyms: Ipamorelin Acetate, NNC 26-0161
Molecular Weight: 711.85 g/mol
CAS Number: 170851-70-4
PubChem ID: 9832483
Appearance: Lyophilized White Powder
Purity: >99% (HPLC Verified)
Shelf Life: 36 months (Store at -20°C for long term)